Many Republicans lost their seats last night.
The win was not only monumental because Roem is the first trans person elected, but also because she won the election over someone who is vocally homophobic and transphobic.
And another transgender woman broke a glass ceiling on Tuesday - Lisa Middleton, who was elected to city council in Palm Springs and became California's first openly transgender non-judicial elected official. The race was one of the year's most high profile, drawing worldwide attention and big money to the northern Virginia House of Delegates district outside the nation's capital.
Roem raised $500,000 in donations, much of it coming from LGBT advocates and other supporters across the country, out raising Marshall 3-1, the Washington Post reported.
Roem has said she did not enter politics to become an LGBTQ symbol but to deal with municipal and infrastructure issues, particularly traffic congestion in her district.
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"To every person who's ever been singled out, who's ever been stigmatised, who's ever been the misfit, who's ever been the kid in the corner, who's ever needed someone to stand up for them when they didn't have a voice of their own because there was no-one else who was with them - this one's for you".
Roem is a journalist who worked for nine years reporting for the Gainesville Times and Price William Times.
He also introduced a bill that would have banned transgender school students from using the bathrooms of their choice. "Though we all wish tonight would have turned out differently, I am deeply grateful for your support and effort over the years".
That message hit the sweet spot, as Roem handily ousted the incumbent Republican by almost 10 percentage points, and established a model for future transgender politicians to follow. The victor is preceded by Althea Garrison, who was outed as transgender after her 1992 election.
"2017 will be remembered as the year of the trans candidate - and Danica's heroic run for office the centerpiece of that national movement", Aisha C. Moodie-Mills, president & CEO of Victory Fund, said in a statement.